Search results for "Perfluoroalkyl heterocyclic ligand"

showing 2 items of 2 documents

Mononuclear Perfluoroalkyl-Heterocyclic Complexes of Pd(II): Synthesis, Structural Characterization and Antimicrobial Activity

2020

Two mononuclear Pd(II) complexes [PdCl2(pfptp)] (1) and [PdCl2(pfhtp)] (2), with ligands 2-(3-perfluoropropyl-1-methyl-1,2,4-triazole-5yl)-pyridine (pfptp) and 2-(3-perfluoroheptyl-1-methyl-1,2,4-triazole-5yl)-pyridine (pfhtp), were synthesized and structurally characterized. The two complexes showed a bidentate coordination of the ligand occurring through N atom of pyridine ring and N4 atom of 1,2,4-triazole. Both complexes showed antimicrobial activity when tested against both Gram-negative and Gram-positive bacterial strains.

Denticityperfluoroalkyl heterocyclic ligandsSpectrophotometry InfraredStereochemistryProton Magnetic Resonance SpectroscopyPharmaceutical ScienceMicrobial Sensitivity TestsSettore BIO/19 - Microbiologia GeneraleRing (chemistry)Analytical Chemistrylcsh:QD241-441chemistry.chemical_compoundlcsh:Organic chemistryAnti-Infective AgentsHeterocyclic CompoundsDrug DiscoveryPyridinemononuclear palladium complexesSettore BIO/06 - Anatomia Comparata E CitologiaPhysical and Theoretical ChemistrytriazolesFluorocarbonsantimicrobial activityBacteriaChemistryLigandCommunicationnarcosisOrganic ChemistrySettore CHIM/06 - Chimica OrganicaDNAAntimicrobialSettore CHIM/03 - Chimica Generale E InorganicaChemistry (miscellaneous)Molecular MedicinePalladiumPlasmidsMolecules
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Synthesis, structural characterization, anti-proliferative and antimicrobial activity of binuclear and mononuclear Pt(II) complexes with perfluoroalk…

2018

Abstract In this paper we report the synthesis of four Pt(II) complexes with 5-perfluoroalkyl-1,2,4-oxadiazolyl-pyridine and 3-perfluoroalkyl-1-methyl-1,2,4-triazolyl-pyridine ligands. Two binuclear complexes [PtCl(pfibap)2](µ-Cl)2 (1), [Pt2(µ-Cl)2(pfioap)4]Cl2 (2), and two mononuclear [PtCl2(pfptp)] (3), [PtCl2(pfhtp)2] (4), were synthesized with the ligands: 2-(5-perfluoropropyl)-1,2,4-oxadiazole-3yl)-pyridine (pfpop), 2-(5-perfluoroheptyl-1,2,4-oxadiazole-3yl)-pyridine (pfhop), 2-(3-perfluoropropyl-1-methyl-1,2,4-triazole-5yl)-pyridine (pfptp), 2-(3-perfluoroheptyl-1-methyl-1,2,4-triazole-5yl)-pyridine (pfhtp), and were structurally characterized. All complexes were tested in vitro on th…

Materials Chemistry2506 Metals and AlloysPopulationAntimicrobial activityPerfluoroalkyl heterocyclic ligandSettore BIO/19 - Microbiologia Generale010402 general chemistrymedicine.disease_cause01 natural sciencesKocuria rhizophilaInorganic ChemistryHeLachemistry.chemical_compoundMaterials ChemistrymedicinePhysical and Theoretical ChemistryBinuclear and mononuclear platinum complexeeducationEscherichia colieducation.field_of_studybiology010405 organic chemistryChemistrybiology.organism_classificationAntimicrobialMolecular biologyIn vitro0104 chemical sciencesApoptosisAntitumor activityDNAInorganica Chimica Acta
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